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As the number of individuals smoking cigarettes in California has decreased, so has the total amount of cigarette purchases by California consumers

The harmful chemicals in cigarettes can damage blood vessels, leading to the narrowing and hardening of arteries

The underlying mechanisms of PM 2

16 , by addressing the dose-dependent properties of mainstream tobacco smoke exposure on allergic response, highlighted the exposure regimen as a critical parameter in the outcome of cigarette smoking on the asthmatic phenotype in these models