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The concentrations of cotinine in serum samples were measured by an isotope-dilution high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometric (ID HPLC-APIC MS/MS) method

And while six episodes may seem like a short amount of time to spend with Mulder and Scully, Duchovny specified that the event series wouldnt necessarily end the franchise: I would be open to doing another cycle