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The Boston Children's Hospital health blog also cautions that many consumers assume "tobacco-free" automatically means "safe" which isn't accurate

Nicotine Withdrawal Inform patients that quitting smoking, with or without CHANTIX, may be associated with nicotine withdrawal symptoms (including depression or agitation) or exacerbation of pre-existing psychiatric illness

This does not make smokeless tobacco safe, however

Accumulating evidence indicates that smoking-related dysbiosis extends beyond periodontitis, contributing to caries, recurrent aphthous stomatitis (RAS), and oral squamous cell carcinoma (OSCC)

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