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The paper, published today in Nicotine and Tobacco Research , has estimated that in September 2013, there were around 151,200 exclusive non-cigarette tobacco users, but by September 2023, this figure had soared to around 772,800
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More recent evidence from a sample of young adult smokers suggests that polymorphisms in the genes encoding the neuronal cholinergic nicotinic subunit receptors, specifically in the genomic region containing the CHRNA5/A3/B4 gene cluster, is a significant predictor of the age of initiation of cigarette smoking (Schlaepfer et al
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