doi:10.1016/j.addbeh.2017.04.007 9
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These findings highlight the MKK3p38 MAPKPRKN pathway as a mechanistic link between cigarette smoke exposure, mitophagy disruption, and epithelial senescence in COPD
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Later, a comprehensive review by Upadhyaya and colleagues (2002) found that psychiatric comorbidity is common in adolescent cigarette smokers, especially among those with disorders involving disruptive behavior (such as oppositional defiant disorder, conduct disorder, and ADHD), major depressive disorders, and drug and alcohol use