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Large-scale clinical studies on the relationship between serum uric acid (sUA) and cardiovascular diseases started from the Framingham Heart Study in the 1980s, the results of which indicate that UA does not have a causal role in the development of coronary heart disease (CHD), death from cardiovascular disease or all causes (Kuwabara et al., 2017a

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Similarly, reimbursement for preventive visits varies greatly among payors and benefits packages

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