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The blend focuses around the familys Criollo 98 seed, using tobaccos from each of the major growing regions of Nicaragua (Condega, Estel, Jalapa, and Ometepe)

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Furthermore, tobacco smoke induced lower airway dysbiosis in COPD, enriching oral commensals and promoting inflammatory pathways involving IL-17, IL-6, ERK/MAPK, and PI3K

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Masking tobacco smoke harshness with flavours contributes to promoting and sustaining tobacco use