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Pros: No nicotine, no tobacco, provides a mild energy boost, familiar pouch format Cons: Caffeine sensitivity may be an issue for some, doesn't replicate the nicotine "hit" Best for: People quitting nicotine who still want a stimulant effect, or anyone seeking an afternoon pick-me-up without coffee 4

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This includes a risk of developing anxiety, depression, paranoia, hallucinations, or psychosis, says Akhil Anand, an addiction psychiatrist and clinical assistant professor at the Cleveland Clinic