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Mutations in TLR4 have been linked with a lower incidence of AS and other CVDs (69)

We hypothesize that the gradual reduction of nicotine from progressively lowering nicotine exposure will lead to lower levels of blood nicotine metabolites and nicotine-derived carcinogens, while not affecting overall cigarettes smoked per day Determine the modifying effect of menthol on progressive nicotine content reduction and biomarkers

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Our open design ensures smooth draws, keeping your cigar elevated and away from hazards

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