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Consequently, scientists have not been able to study polymer fume fever in an animal model

Aekplakorn W, Hogan MC, Tiptaradol S, Wibulpolprasert S, Punyaratabandhu P, Lim SS: Tobacco and hazardous or harmful alcohol use in Thailand: Joint prevalence and associations with socioeconomic factors

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This is primarily because no ENDS manufacturers have applied to the FDA to develop their product as a cessation therapy, a prerequisite for conducting clinical trials in the United States