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People who smoke lose an average of 10 years of life compared to those who never smoked

Nicotine clearly acts as a gateway drug on the brain, and this effect is likely to occur whether the exposure comes from smoking cigarettes, passive tobacco smoke, or e-cigarettes. Studies show that the typical e-cigarette user is a long-term smoker who has been unable to stop smoking

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This difference in delivery can make it challenging to directly compare puffs between the two methods