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It includes the whole spectrum of fatty liver, ranging from simple steatosis to steatohepatitis [non-alcoholic steatohepatitis (NASH)], which can progress to liver cirrhosis and hepatocellular carcinoma ( In the United States, 72% of the adult male population is overweight or obese out of which 11% have a BMI of 35 kg/m 2 and 4% a BMI of at least 40 kg/m 2 ( Mechanisms Linking Nicotine to NAFLD The hallmark of NAFLD is accumulation of triglycerides (TG) in the hepatocytes (steatosis)

Costiniuk CT, Brunet L, Rollet-Kurhajec KC, Cooper CL, Walmsley SL, Gill MJ, et al

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