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The only survey question on vaping is extremely broad, asking: Have you ever used an e-cigarette? By comparison, questions involving combustible tobacco include Do you now smoke cigarettes? and whether someone has smoked at least 100 cigarettes in their life

Although the potential involvement of PINK1-PARK2-independent mitophagy remains to be elucidated, PINK1-PARK2 pathway-mediated mitophagy has been widely implicated in COPD and IPF pathogenesis through regulating cell fate, including programmed cell death, cellular senescence, and myofibroblast differentiation [14, 54]

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