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Nicotine enhanced oxidative stress and activates NF-B [121]

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The risk exists because: Joints come into direct contact with the lips and mouth The paper can absorb moisture from saliva The heat from smoking does not reach high enough temperatures to kill all pathogens Microscopic cuts or abrasions on the lips provide entry points for the virus While the risk is present, it's important to note that many factors influence whether transmission actually occurs in any given situation

As they became richer, they started to smoke more