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In the years following the opening of her modest millinery shop, Gabrielle "Coco" Chanel became a pivotal designer of both fashionable casual wear and Paris haute couture as well as an icon and arbiter of 20th-century style with her bob haircut and pearls

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Need for Additional, Costly Procedures: Failure due to smoking may necessitate additional, complex, and costly procedures such as bone grafting or re-implantation

Its balance can be altered by many environmental factors such as eating habits, the consumption of drugs (such antibiotics) and toxins, including cigarette smoke (1,2)