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They work by delivering small doses of nicotine through the skin or oral ingestion and effectively keep excessive tobacco dependence under control

The message for regulators dealing with newly marketed reduced risk products is that any suggestion of seriously reduced coronary heart disease and stroke from using these products is premature. Deborah Arnott, chief executive of health charity ASH, said: Many smokers think that theyre not at risk if they only smoke one or two a day

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Particularly problematic themes included pooling different SLT-products, failing to account for heterogeneity of studies, pooling studies despite variation in sampling methodologies, and failing to report country-specific results, even when these were available