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66,67 Therefore, miRNAs should not be seen as independent diagnostic markers, but rather as possible parts of multi-marker panels that may better reflect OA heterogeneity, including inflammatory phenotypes that may be more common in smoking-related disease

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At first, the changes were subtle

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Hopefully, if youve gotten to this part of the article youll know the difference, but we thought wed give a short answer to this question just in case you need it