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Doses up to around 400 mg (approximately 3 cups of coffee, 10 cans of cola, or 2 energy drinks) are mostly harmless

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The WHO wants governments to prevent e-cigarette manufacturers from making claims about their products' capacity to improve people's health by helping them quit unless and until they provided "convincing supporting scientific evidence and obtain regulatory approval." There is still only limited evidence that e-cigarettes do help people quit, which "does not allow conclusions to be reached" on that point, it added

Conclusions We have shown moderate levels of drinking (one bottle of wine per week) is associated with a significant increased absolute lifetime risk of alcohol-related cancers in women, driven largely by breast cancer