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iPSC MSCs also attenuate asthma inflammation, protection attributed to mitochondrial transfer via connexin 43 (CX43)-mediated tunneling nanotube (TNT) formation (179)

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It has been known that CS-induced oxidative stress weakened GSH levels in airway epithelium and disrupted tight junctions, epithelial barrier integrity, finally leading to the impairment of epithelial barrier function [45, 46]