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METHODS Protocol and registration The protocol of this study was registered in PROSPERO and conducted in accordance with the methods described in the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines 10,11

The higher pH and moisture content, as well as the lower nitrite levels, allow Swedish snus to deliver more nicotine at less risk of adverse effects than the American brands

In the course of this journey, you will experience anxiety, restlessness, irritability, nervousness, and difficulty sleeping

Forty-five studies were identified (17 Europe, 16 North America, 11 Asia, 1 Australia)

That was as important as anything to me, Perkins said of Gill