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Various targeted sequencing panels have recently been developed to efficiently determine tumour mutation burden, and a strong correlation has been observed between targeted sequencing and whole genome sequencing in some studies.31 32 Another limitation of our study was recall bias, which cannot be ruled out when obtaining smoking information, even in a prospective cohort study
Image Copyright: scyther5 / Shutterstock Research The Japanese Ministry of Health has carried out research which claims that e-cigarettes contain 10 times the level of carcinogens than traditional tobacco products
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