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or (2) Within 180 days after the close of the period in which the qualified article is manufactured or produced

February 2025: Japan Tobacco launched the Ploom X Advanced in Tokyo, incorporating a dual-heating blade that raises tobacco-stick temperature to 295C and delivers nicotine flux comparable to combustible cigarettes while producing 90% fewer harmful compounds according to independent testing by the National Institute of Public Health

Metabolism of Nicotine The liver is an essential organ for detoxification, playing a significant role in metabolizing nicotine, the addictive substance in cigarettes

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