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The adjusted RRs (95% CIs) for overall birth congenital anomalies (defined as having any one of the congenital malformations above significantly associated with maternal cigarette smoking) among women who smoked 15, 610, and 11 cigarettes per day before pregnancy were 1.31 (1.221.41), 1.25 (1.171.33), and 1.35 (1.281.43), respectively