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Fatigue Lack of sleep lowers your immune defences and can contribute to cold sore recurrence

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[46] : 91 The transtheoretical model, including "stages of change", has been used in tailoring smoking cessation methods to individuals, [93] [94] [95] [96] however, there is some evidence to suggest that "stage-based self-help interventions (expert systems and/or tailored materials) and individual counselling are neither more nor less effective than their non-stage-based equivalents." [97] How to set a quit date Most smoking cessation resources such as the Centers for Disease Control and Prevention (CDC) [98] and The Mayo Clinic [99] encourage smokers to create a quit plan, including setting a quit date, which helps them anticipate and plan for smoking challenges