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Although the consumption of tobacco has declined over the past 2-3 years, the north-eastern states of India have been reported to have the highest consumption of tobacco in India

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Nicotine in diseases Smoking inserts a high amount of xenobiotics, which in turn can alkylate DNA, activate specific (anti)inflammatory signals, and oxidative stress in active smokers and also second-hand smokers [167, 168]

The reason for the high rates of smoking among people with mental illnesses may relate to efforts to self-medicate with nicotine