Chewing tobacco effects, such as gum disease, tooth decay, and an increased risk of oral cancer, are well-documented concerns for users
They likely have one or two well-controlled or resolved minor health conditions and no deaths in their immediate family from heart disease or cancer (some carriers allow one death in your immediate family from these conditions)
Additional evidence also supports increases in cardiac inflammation, oxidative stress, and fibrosis after prolonged exposure to electronic cigarettes, which was comparable to damage induced by combustible tobacco products [93]
Two of these prospective within-subject studies assessed changes in oral mucosa amongst current users, consistently reporting a reduction in pre-existing snus-associated lesions or an improvement in lesion severity over short follow-up periods (55, 57)
Addict Behav 2006;31:171621