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Overexpression of neutrophils and macrophages may result in cell and lung tissue damage as well as chronic inflammation, as shown in traditional cigarette smoking and, if unresolved, may lead to fibrosis, impaired lung function and structural changes in the airway (Cheng et al

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Both forms of cigarettes pose serious health hazards, as smoking any form of tobacco has been linked to a variety of health problems, including lung cancer and heart disease