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The methods involved in the mouse COPD model have been described previously [30]
A minimum lethal dose of nicotine in dogs is reported at 4 mg per pound body weight, but clinical signs have been seen at a dose of 0.4mg per pound body weight
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Data collection The eligible participants in this study were visited at their homes by trained community healthcare workers who obtained written informed consent from the participants, administered a pre-tested structured questionnaire, performed physical examinations, and collected anthropometric measurements
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