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The Dopamine Dilemma: ADHD and the Craving for Reward At the heart of ADHD lies a neurochemical imbalance , particularly involving dopamine , the brain's primary neurotransmitter responsible for pleasure, reward, and motivation

a) Irritation and Inflammation The moment smoke enters your mouth, it irritates the delicate lining of your throat.Thousands of dangerous substances, including tar, nicotine, and carbon monoxide , are found in cigarette smoke and cause tissue inflammation

If youre a rapid metabolizer, youll smoke more frequently, accelerating receptor changes

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Primack BA, Soneji S, Stoolmiller M, Fine MJ, Sargent JD (2015) Progression to traditional cigarette smoking after electronic cigarette use among us adolescents and young adults