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Different types of wicking material, varying in size and shape, have been used in e-cigarettes 3,13

IL-4 tends to be reduced in people with gum disease and increases after treatment, which suggests that certain bacteria in the mouths of e-cigarette users may be actively suppressing immune responses

Light cigarettes typically deliver a lighter tobacco taste and a smoother smoking experience, making them less intense than full flavour cigarettes

The synergistic interaction between nicotine and acetaldehyde is substantiated by experiments where the combination of nicotine and acetaldehyde results in a rewarding effect that exceeds the additive effects of each substance in rats (Philip Morris 1992)

Tolerance and Nicotine Dependency Individual factors such as nicotine tolerance and dependency also play a role in determining puff equivalency