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Although FDA announced prioritized enforcement of required pre-market authorization for all ENDS products, the agency was unable to regulate ENDS products created with synthetic nicotine until Congress enacted a new law in April 2022 granting FDA authority to regulate tobacco products containing nicotine of any source

Lightweight construction reduces per-unit material cost at volumes where fractions of a cent per box compound across millions of units

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The law also gives the government broader authority to regulate tobacco and vaping products, including control over flavors, packaging, and advertising

CO, heart rate (HR), systolic and diastolic blood pressure (BP) and subjective effects were measured pre- (10) and at 10, 30, 40 and 70 min post-drug