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there is a strong dose-dependent relationship between smoking and the risk of ischemic stroke, with 12% higher chances of an acute cerebrovascular event with every increment of 5 cigarettes per day 6 Ischemic stroke is not the only type of stroke associated with tobacco usage, an increased risk was also observed for ICH and subarachnoid hemorrhage (SAH)

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The Report on Carcinogens (RoC) identifies 2 groups of agents: The 15th edition of the RoC includes about 250 substances and exposures

Nicotine ( C 10 H 14 N 2 ), a potent parasympathomimetic alkaloid, is the primary addictive tobacco smoke component