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The chromatographic procedures involved the use of a C 18 column (50 4.6 mm, 0.5 m) with 75% acetonitrile and 0.05% formic acid as mobile phase in an isocratic elution at a flow rate of 0.3 ml/min in a total run time of 4 min

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However, the number of deaths caused by smoking has been decreasing : in 2018 there were 77,000, in 2009 there were 82,000 (NHS Digitals Statistics on Smoking, England 2020)

Recent studies have indicated that acrolein modification induces functional defects in its targets, such as extracellular matrix (ECM) protein 7 , apolipoprotein E 8 and protein disulphide isomerase, during CS exposure 9

Smoke detectors come in various forms, and sensitivity is one of the important factors