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A century later the naturalist Carl Linnaeus named the genus of cultivars Nicotiana in his honor, the source of the word nicotine in modern parlance.

and Federal Ave

22 The absence of ABCA1 or ABCG1 in alveolar type II epithelial cells leads to cholesterol overload, impairing surfactant function, and resulting in severe surfactant protein and lipid accumulation

Chronic smoking also leads to the formation of atheromatous plaques due to increased expression of matrix metalloproteinases (MMP), particularly MMP-12 and MMP-9 in macrophages, MMP-8 and MMP-9 in endothelial cells, and MMP-2 and MMP-9 in vascular smooth muscle cells ( 35 , 36 )

Below we see how the Deluxe headstock looked initially