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If the production of gas phase toxins increases less than the increase in TPM, then exposing the rats to a fixed amount of TPM will reduce exposure to the gaseous constituents

Alcohol consumption, particularly in combination with smoking, synergistically elevates the risk, as ethanol acts as a solvent for tobacco carcinogens, enhancing their absorption in the laryngeal mucosa 21

While cigarette smoking is a major cause of heart disease, the report concluded its unclear whether marijuana use is associated with heart attacks or strokes

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