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Protein quantification and generation of the heatmap was performed using perSPECtives 2.0.6 (Proteome Software Inc.) by summarizing the intensities of identified precursor ions for each protein as protein intensities

FDA has identified the root causes of investigator attrition and has some strategies underway to address them, but the agency has not developed action plans that address all the identified root causes, due in large part to the fact that implementing such plans would reduce capacity to conduct inspections

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