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The following section outlines the recommended usage and limits for common Nicotine Replacement Therapy (NRT) options: [17][18] Nicotine gum: It is typically used every 12 hours, with a maximum of 24 pieces per day

While a recent cohort study demonstrated a significant trend of increasing stroke risk with younger age at smoking initiation over a ten-year follow-up 25 , no such association with stroke was identified in a birth cohort followed up for five decades 26

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It continues with a section on the use of electronic smoking devices and concludes by looking at exposure to tobacco smoke

PMID 12090453