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Some of the most harmful include: Carbon monoxide Formaldehyde Benzene Nitrogen oxides Benzo[a]pyrene Hydrogen Cyanide These contaminants behave differently from particles

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Notably, some populations of AMs might adopt a mixed or alternative (M2-like) activation state, potentially relying on oxidative phosphorylation to varying degrees, which could paradoxically contribute to impaired bacterial clearance and fibrotic repair processes, thus driving disease progression

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