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For some, nicotine abstinence may actually worsen symptoms of mental disorders.[10] Moreover, about 20 years ago, major tobacco US manufacturers recognized that a large proportion of their customer population was individuals with underlying psychiatric disorders
CB1 and CB2 share 44% amino acid homology and are G protein-coupled receptors (GPCRs)
Reduced REM leads to irritability, poor focus, and emotional instability
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The association was stronger among boys than among girls and was mediated by adolescents own cigarette and alcohol use
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