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Genetic susceptibility, DNA methylation changes, local chronic lung inflammation, and abnormal repair mechanisms in COPD patients are important potential factors for lung cancer development [58,59,60]

The prevalence of e-cigarette use has been increasing among adolescents and adults in both the US8 and Europe.9 In adults, the highest prevalence is in current conventional cigarette smokers, of whom 31% report having tried electronic cigarettes.9 There are few studies documenting use trends in older smokers and none in individuals with established smoking-induced lung disease such as chronic obstructive pulmonary disease (COPD)

THE COST OF CONFISCATING DISPOSABLE E-CIGARETTES In 2020, New York City outlawed the vast majority of e-cigarette types, banning flavors that can appeal to youngsters

Hutzler, C

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