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The prospectively observed rate of cardiovascular malformations in pregnancies with exposure to bupropion in the first trimester from the international Pregnancy Registry was 1.3% (9 cardiovascular malformations/675 first trimester maternal bupropion exposures), which is similar to the background rate of cardiovascular malformations (approximately 1%)

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Oral Contraceptives High estrogen levels from oral contraceptives may disrupt normal healing processes and increase the risk of dry socket

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9.4 MAC BAREN 9.4.1 COMPANY OVERVIEW 9.4.2 COMPANY INSIGHTS