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Devices like IQOS, Glo, and Ploom have seen widespread adoption in developed nations, with IQOS accounting for over 18 million users globally by the end of 2024

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Over time, hypertension can damage blood vessels, the heart, kidneys, and brain

But in the case of e-cigarettes, such concerns may be particularly trenchant: though the CDC has declined to provide specific numbers, as Rolling Stone previously reported, many of the more than 300 recent cases of lung ailments attributed to vaping that are being investigated by the CDC have been the result of young people purchasing black-market THC cartridges, not mass-produced e-cigarettes from companies like Juul

Manufacturers might release the final run of the original recipe as a "Farewell Edition," defining the limitation by the impending extinction of the formula