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Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: March 11, 2026 Research suggests a potential connection: chronic gastritis may damage the stomachs nerves and muscles responsible for moving food, which can lead to delayed gastric emptying, the hallmark of gastroparesis

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Through its interaction with acetylcholine receptors, nicotine can modulate signaling pathways that link mental state to immune activity

Interpretation of the relevant studies is complicated by the lack of adequate, validated measures of dependence for use in adolescent smokers (Colby et al