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A large, new meta-analysis published in The BMJ found that smoking just one cigarette a day could drastically increase the risk of coronary heart disease and stroke

Regarding cardiovascular health, if someone switches from smoking to vaping completely, it's almost certainly a good change

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Before now, we had a large body of epidemiological evidence linking smoking with cancer, but now we can actually observe and quantify the molecular changes in the DNA due to cigarette smoking, explains Dr Ludmil Alexandrov, the first author from Los Alamos National Laboratory