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Considering that combustible cigarettes are the most harmful class of tobacco products, alternative tobacco products that do not generate combustion-related toxicants have been suggested as less harmful alternatives for smokers who choose not to quit smoking as part of a comprehensive harm reduction strategy 2,3

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The principal transporter of glinides is the Organic Anion Transporting Polypeptide (OATP) 1B1

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and (3) pro-apoptotic genes, such as Tspo and Bid , which would decrease the probably of apoptosis occurring