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Donaldson SI, Dormanesh A, Perez C, et al

Table 3 Incidence and aHR of Developing CD According to Smoking Status and Onset Age of Smoking Subgroup analyses Subgroup analyses evaluated whether the relationship between the onset age of smoking and the risk of UC was influenced by sex, BMI, metabolic syndrome, alcohol consumption, or regular exercise after adjusting for age, sex, income, alcohol consumption, regular exercise, BMI, metabolic syndrome, and peak year of smoking

However, if the choice is to do nothing or vape, you should absolutely do nothing