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Two users placing a 6mg pouch under their lip will not have identical experiences because individual factors like saliva production, gum permeability, and pouch placement all influence how much actually reaches the bloodstream

We started gathering all the data we could find, Sheltzer says, explaining that he and Smith focused first on comparing gene activity in the lungs across different ages, between the sexes, and between smokers and nonsmokers

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If e-cigarettes help smokers make that change, they are reducing tobacco-related harm

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