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In some cases, other nicotine metabolites, such as nicotine-1-N-oxide, trans-3-hydroxycotinine, or nornicotine, or other tobacco chemicals, such as anabasine in urine, may also be tested

Casey Harvell, public policy director for the American Lung Association Massachusetts, says the price hike will encourage 25,000 smokers to quit, and prevent 27,000 children from taking up smoking in the first place

This is sometimes called combination nicotine therapy and is a well-documented approach [1]

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