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For FDA to revoke a standard, the agency must find that the standard is "no longer appropriate for the protection of public health." 93 When enacting the TCA, Congress recognized that flavors, specifically, can make tobacco products more appealing to youth and expose tobacco users to additional carcinogens or other toxic constituents

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5.2 Therapeutic potential The reversible nature of epigenetic alterations gives crucial therapeutic windows for cervical cancer as well as HPV-driven malignancies

"Researchers discovered that cigarette smoke was potentially dangerous to cells at lower and higher concentrations compared to e-cigarettes, which were only toxic at higher levels." Companies that sell the devices, however, say that since the tobacco is heated and not burned they produce 95 percent lower levels of toxic compounds

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