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This proposed lineage relationship between tuft-like cells, ionocytes, and PNECs may relate to our observation of an age-dependent balance of rare cell ratios and the recently reported tuft-like variants of small cell lung cancer, generally thought to be a PNEC-derived tumor 58

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Each pack comprises 20 units within 1 box, exclusively compatible with IQOS ILUMA and IQOS ILUMA PRIME devices featuring the Smartcore Induction System